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A 20% increase in nitrogen-use efficiency in the world’s cereal production methods would scale back the worldwide manufacturing of reactive nitrogen by roughly 6% and result in reduced expenditure for fertilizers equivalent to a value of about US$ 5 billion yearly. Anthropogenic sources of nitrogen—from the manufacturing of artificial fertilizer, fossil gasoline combustion and by nitrogen-fixing crops and timber in agroecosystems—now exceed pure terrestrial sources, such that greater than half   The rate of increase in the manufacturing of reactive nitrogen has accelerated sharply since 1960 (Figure 2.15).   Australian scientists have detected what they assume is an evolutionary response to fast local weather change amongst the fruitfly Drosophila—a species that often used in genetic experiments.